Pyruvate Decarboxylase, the Target for Omeprazole in Metronidazole-Resistant and Iron-Restricted Tritrichomonas foetus

The substituted benzimidazole omeprazole, used for the treatment of human peptic ulcer disease, inhibits the growth of the metronidazole-resistant bovine pathogen Tritrichomonas foetus in vitro (MIC at which the growth of parasite cultures is inhibited by 50%, 22 μg/ml [63 μM]). The antitrichomonad...

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Bibliographic Details
Main Authors: Sutak, Róbert, Tachezy, Jan, Kulda, Jaroslav, Hrdý, Ivan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
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Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC415579/
https://ncbi.nlm.nih.gov/pubmed/15155220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2185-2189.2004
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