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Alternative Pathway of Metronidazole Activation in Trichomonas vaginalis Hydrogenosomes

Metronidazole and related 5-nitroimidazoles are the only available drugs in the treatment of human urogenital trichomoniasis caused by the protozoan parasite Trichomonas vaginalis. The drugs are activated to cytotoxic anion radicals by their reduction within the hydrogenosomes. It has been establish...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hrdý, Ivan, Cammack, Richard, Stopka, Pavel, Kulda, Jaroslav, Tachezy, Jan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315937/
https://ncbi.nlm.nih.gov/pubmed/16304169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.12.5033-5036.2005
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