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Alternative Pathway of Metronidazole Activation in Trichomonas vaginalis Hydrogenosomes
Metronidazole and related 5-nitroimidazoles are the only available drugs in the treatment of human urogenital trichomoniasis caused by the protozoan parasite Trichomonas vaginalis. The drugs are activated to cytotoxic anion radicals by their reduction within the hydrogenosomes. It has been establish...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1315937/ https://ncbi.nlm.nih.gov/pubmed/16304169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.12.5033-5036.2005 |
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