Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells

BACKGROUND: The development of immunotherapy has led to significant progress in the treatment of metastatic cancer, including the development of genetic engineering technologies that redirect lymphocytes to recognize and target a wide variety of tumor antigens. Chimeric antigen receptors (CARs) are...

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Main Authors: Beard, Rachel E, Zheng, Zhili, Lagisetty, Kiran H, Burns, William R, Tran, Eric, Hewitt, Stephen M, Abate-Daga, Daniel, Rosati, Shannon F, Fine, Howard A, Ferrone, Soldano, Rosenberg, Steven A, Morgan, Richard A
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155770/
https://ncbi.nlm.nih.gov/pubmed/25197555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-1426-2-25
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