Validation of Genetically Matched Wild Type Strain and Lysyl Oxidase- Like 1 Knockout Mouse Model of Pelvic Organ Prolapse

OBJECTIVES: Lysyl oxidase-like 1 knockout (Loxl1(−/−)) mice demonstrate deficient elastin homeostasis associated with pelvic organ prolapse (POP). To further investigate the pathophysiology of POP in these animals, a genetically-matched homozygous positive (Loxl1(+/+)) or wild type strain is needed....

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Detaylı Bibliyografya
Asıl Yazarlar: Couri, Bruna M., Borazjani, Ali, Lenis, Andrew T., Balog, Brian, Kuang, Mei, Lin, Dan Li, Damaser, Margot S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155759/
https://ncbi.nlm.nih.gov/pubmed/25181380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SPV.0000000000000104
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