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Validation of Genetically Matched Wild Type Strain and Lysyl Oxidase- Like 1 Knockout Mouse Model of Pelvic Organ Prolapse
OBJECTIVES: Lysyl oxidase-like 1 knockout (Loxl1(−/−)) mice demonstrate deficient elastin homeostasis associated with pelvic organ prolapse (POP). To further investigate the pathophysiology of POP in these animals, a genetically-matched homozygous positive (Loxl1(+/+)) or wild type strain is needed....
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4155759/ https://ncbi.nlm.nih.gov/pubmed/25181380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SPV.0000000000000104 |
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