Determination of the In Vivo Pharmacodynamic Profile of Cefepime against Extended-Spectrum-Beta-Lactamase-Producing Escherichia coli at Various Inocula

Cefepime was evaluated in vivo against two inoculum sizes of four strains of Escherichia coli that produced extended-spectrum beta-lactamases (ESBLs) in a murine neutropenic thigh infection model to characterize the pharmacodynamic activity of cefepime in the presence of ESBL-producing bacteria and...

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Autori principali: Maglio, Dana, Ong, Christine, Banevicius, Mary Anne, Geng, Qiuming, Nightingale, Charles H., Nicolau, David P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC415572/
https://ncbi.nlm.nih.gov/pubmed/15155182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.1941-1947.2004
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