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Practical strategies for the evaluation of high-affinity protein/nucleic acid interactions

The quantitative evaluation of binding interactions between proteins and nucleic acids is highly sensitive to a variety of experimental conditions. Optimization of these conditions is critical for obtaining high quality, reproducible data, particularly in the context of very high affinity interactio...

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Detalhes bibliográficos
Main Authors: Altschuler, Sarah E., Lewis, Karen A., Wuttke, Deborah S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155600/
https://ncbi.nlm.nih.gov/pubmed/25197549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/jnai.2013.e3
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