Aldehyde Dehydrogenase Expression Drives Human Regulatory T Cell Resistance to Posttransplantation Cyclophosphamide

High-dose, posttransplantation cyclophosphamide (PTCy) is an effective strategy for preventing graft-versus-host disease (GVHD) after allogeneic blood or marrow transplantation (alloBMT). However, the mechanisms by which PTCy modulates alloimmune responses are not well understood. We studied early T...

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Hauptverfasser: Kanakry, Christopher G., Ganguly, Sudipto, Zahurak, Marianna, Bolaños-Meade, Javier, Thoburn, Christopher, Perkins, Brandy, Fuchs, Ephraim J., Jones, Richard J., Hess, Allan D., Luznik, Leo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155575/
https://ncbi.nlm.nih.gov/pubmed/24225944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006960
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