Učitavanje...
Situational aldehyde dehydrogenase expression by regulatory T cells may explain the contextual duality of cyclophosphamide as both a pro-inflammatory and tolerogenic agent
In two recent publications, we demonstrated that after allogeneic stimulation, regulatory T cells (T(regs)) increase expression of aldehyde dehydrogenase (ALDH), the major in vivo mechanism of cyclophosphamide detoxification, thereby becoming cyclophosphamide resistant. Differential ALDH expression...
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| Izdano u: | Oncoimmunology |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4404790/ https://ncbi.nlm.nih.gov/pubmed/25949893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.974393 |
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