Decreased exposure of simvastatin and simvastatin acid in a rat model of type 2 diabetes

AIM: Simvastatin is frequently administered to diabetic patients with hypercholesterolemia. The aim of the study was to investigate the pharmacokinetics of simvastatin and its hydrolysate simvastatin acid in a rat model of type 2 diabetes. METHODS: Diabetes was induced in 4-week-old rats by a treatm...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Xu, Dan, Li, Feng, Zhang, Mian, Zhang, Ji, Liu, Can, Hu, Meng-yue, Zhong, Ze-yu, Jia, Ling-ling, Wang, Da-wei, Wu, Jie, Liu, Li, Liu, Xiao-dong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155525/
https://ncbi.nlm.nih.gov/pubmed/25152023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.39
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados