Generation and characterization of influenza A viruses with altered polymerase fidelity

Genetic diversity of influenza A viruses (IAV) acquired through the error-prone RNA-dependent RNA polymerase (RdRP) or genetic reassortment enables perpetuation of IAV in humans through epidemics or pandemics. Here, to assess the biological significance of genetic diversity acquired through RdRP, we...

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Autores principales: Cheung, Peter PH, Watson, Simon J., Choy, Ka-Tim, Sia, Sin Fun, Wong, Diana DY, Poon, Leo LM, Kellam, Paul, Guan, Yi, Peiris, JS Malik, Yen, Hui-Ling
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155405/
https://ncbi.nlm.nih.gov/pubmed/25183443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5794
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