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Lenalidomide, an antiproliferative CLL drug
In this issue of Blood, Fecteau et al show that lenalidomide inhibits proliferation of chronic lymphocytic leukemia (CLL) cells in vitro by targeting cereblon. Thus far, the clinical activity of this drug in CLL was believed to be mainly via the microenvironment.(1)
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4155263/ https://ncbi.nlm.nih.gov/pubmed/25190749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-587360 |
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