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MDSCs: the final frontier of the microenvironment in CLL?
In this issue of Blood, Jitschin et al identify increased numbers of myeloid-derived suppressor cells (MDSCs) in untreated patients with chronic lymphocytic leukemia (CLL) suppressing T cells and inducing regulatory T cells (T(regs)), resulting in impaired immune responses.(1)
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118477/ https://ncbi.nlm.nih.gov/pubmed/25082859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-578880 |
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