MIPgen: optimized modeling and design of molecular inversion probes for targeted resequencing

Summary Molecular inversion probes (MIPs) enable cost-effective multiplex targeted gene resequencing in large cohorts. However, the design of individual MIPs is a critical parameter governing the performance of this technology with respect to capture uniformity and specificity. MIPgen is a user-frie...

Full description

Saved in:
Bibliographic Details
Main Authors: Boyle, Evan A., O’Roak, Brian J., Martin, Beth K., Kumar, Akash, Shendure, Jay
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Applications Notes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155255/
https://ncbi.nlm.nih.gov/pubmed/24867941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu353
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items