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MPBind: a Meta-motif-based statistical framework and pipeline to Predict Binding potential of SELEX-derived aptamers

Summary: Aptamers are ‘synthetic antibodies’ that can bind to target molecules with high affinity and specificity. Aptamers are chemically synthesized and their discovery can be performed completely in vitro, rather than relying on in vivo biological processes, making them well-suited for high-throu...

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Detalhes bibliográficos
Main Authors: Jiang, Peng, Meyer, Susanne, Hou, Zhonggang, Propson, Nicholas E., Soh, H. Tom, Thomson, James A., Stewart, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155251/
https://ncbi.nlm.nih.gov/pubmed/24872422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu348
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