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Isolation of a temperature-sensitive dengue-2 virus under conditions suitable for vaccine development.

Dengue virus, type 2, in viremic human sera and after passage in cell cultures produces mixtures of small and large plaques when assayed in LLC-MK2 cells. Clones of dengue virus type 2 obtained by plaque selection in primary green monkey kidney cell cultures were tested for temperature sensitivity i...

詳細記述

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主要な著者: Eckels, K H, Brandt, W E, Harrison, V R, McCown, J M, Russell, P K
フォーマット: Artigo
言語:Inglês
出版事項: 1976
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC415517/
https://ncbi.nlm.nih.gov/pubmed/977127
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