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Molecular Pathways: Targeting ETS Gene Fusions in Cancer
Rearrangements, or gene fusions, involving the ETS family of transcription factors are common driving events in both prostate cancer and Ewing’s sarcoma. These rearrangements result in pathogenic expression of the ETS genes, and trigger activation of transcriptional programs enriched for invasion an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4155001/ https://ncbi.nlm.nih.gov/pubmed/24958807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0275 |
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