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ACVR1 mutations in DIPG: lessons learned from FOP

Whole genome sequencing studies have recently identified a quarter of cases of the rare childhood brainstem tumour diffuse intrinsic pontine glioma (DIPG) to harbour somatic mutations in ACVR1. This gene encodes the type I BMP receptor ALK2, with the residues affected identical to those which, when...

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Bibliografische gegevens
Hoofdauteurs: Taylor, Kathryn R, Vinci, Maria, Bullock, Alex N, Jones, Chris
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154859/
https://ncbi.nlm.nih.gov/pubmed/25136070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1298
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