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ACVR1 mutations in DIPG: lessons learned from FOP
Whole genome sequencing studies have recently identified a quarter of cases of the rare childhood brainstem tumour diffuse intrinsic pontine glioma (DIPG) to harbour somatic mutations in ACVR1. This gene encodes the type I BMP receptor ALK2, with the residues affected identical to those which, when...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4154859/ https://ncbi.nlm.nih.gov/pubmed/25136070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1298 |
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