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Disentangling Pooled Triad Genotypes for Association Studies

Association studies that genotype affected offspring and their parents (triads) offer robustness to genetic population structure while enabling assessments of maternal effects, parent-of-origin effects, and gene-by-environment interaction. We propose case-parents designs that use pooled DNA specimen...

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Detalhes bibliográficos
Main Authors: Shi, Min, Umbach, David M., Weinberg, Clarice R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154801/
https://ncbi.nlm.nih.gov/pubmed/24962618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12073
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