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Molecular Imaging of Phosphorylation Events for Drug Development

PURPOSE: Protein phosphorylation mediated by protein kinases controls numerous cellular processes. A genetically encoded, generalizable split firefly luciferase (FL)-assisted complementation system was developed for noninvasive monitoring phosphorylation events and efficacies of kinase inhibitors in...

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Bibliographic Details
Main Authors: Chan, C. T., Paulmurugan, R., Reeves, R. E., Solow-Cordero, D., Gambhir, S. S.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154800/
https://ncbi.nlm.nih.gov/pubmed/19048345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-008-0187-7
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