Inhibition of cAMP-Activated Intestinal Chloride Secretion by Diclofenac: Cellular Mechanism and Potential Application in Cholera

Cyclic AMP-activated intestinal Cl(−) secretion plays an important role in pathogenesis of cholera. This study aimed to investigate the effect of diclofenac on cAMP-activated Cl(−) secretion, its underlying mechanisms, and possible application in the treatment of cholera. Diclofenac inhibited cAMP-a...

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Hlavní autoři: Pongkorpsakol, Pawin, Pathomthongtaweechai, Nutthapoom, Srimanote, Potjanee, Soodvilai, Sunhapas, Chatsudthipong, Varanuj, Muanprasat, Chatchai
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154654/
https://ncbi.nlm.nih.gov/pubmed/25188334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003119
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