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Revealing Molecular Mechanisms by Integrating High-Dimensional Functional Screens with Protein Interaction Data
Functional genomics screens using multi-parametric assays are powerful approaches for identifying genes involved in particular cellular processes. However, they suffer from problems like noise, and often provide little insight into molecular mechanisms. A bottleneck for addressing these issues is th...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4154648/ https://ncbi.nlm.nih.gov/pubmed/25188415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003801 |
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