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BMP Suppresses PTEN Expression via RAS/ERK Signaling

Bone morphogenetic protein (BMP), a member of the transforming growth factor β family, classically utilizes the SMAD signaling pathway for its growth suppressive effects, and loss of this signaling cascade may accelerate cell growth. In the colon cancer predisposition syndrome Juvenile Polyposis, as...

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Bibliografiske detaljer
Main Authors: Beck, Stayce E., Carethers, John M.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154563/
https://ncbi.nlm.nih.gov/pubmed/18059158
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