Differential contribution of TRPM4 and TRPM5 nonselective cation channels to the slow afterdepolarization in mouse prefrontal cortex neurons

In certain neurons from different brain regions, a brief burst of action potentials can activate a slow afterdepolarization (sADP) in the presence of muscarinic acetylcholine receptor agonists. The sADP, if suprathreshold, can contribute to persistent non-accommodating firing in some of these neuron...

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Hlavní autoři: Lei, Ya-Ting, Thuault, Sebastien J., Launay, Pierre, Margolskee, Robert F., Kandel, Eric R., Siegelbaum, Steven A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154465/
https://ncbi.nlm.nih.gov/pubmed/25237295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00267
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