Cocaine inhibition of nicotinic acetylcholine receptors influences dopamine release

Nicotinic acetylcholine receptors (nAChRs) potently regulate dopamine (DA) release in the striatum and alter cocaine's ability to reinforce behaviors. Since cocaine is a weak nAChR inhibitor, we hypothesized that cocaine may alter DA release by inhibiting the nAChRs in DA terminals in the stria...

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Bibliografiske detaljer
Main Authors: Acevedo-Rodriguez, Alexandra, Zhang, Lifen, Zhou, Fuwen, Gong, Suzhen, Gu, Howard, De Biasi, Mariella, Zhou, Fu-Ming, Dani, John A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154440/
https://ncbi.nlm.nih.gov/pubmed/25237305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2014.00019
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