Cocaine inhibition of nicotinic acetylcholine receptors influences dopamine release

Nicotinic acetylcholine receptors (nAChRs) potently regulate dopamine (DA) release in the striatum and alter cocaine's ability to reinforce behaviors. Since cocaine is a weak nAChR inhibitor, we hypothesized that cocaine may alter DA release by inhibiting the nAChRs in DA terminals in the stria...

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Detalhes bibliográficos
Main Authors: Acevedo-Rodriguez, Alexandra, Zhang, Lifen, Zhou, Fuwen, Gong, Suzhen, Gu, Howard, De Biasi, Mariella, Zhou, Fu-Ming, Dani, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154440/
https://ncbi.nlm.nih.gov/pubmed/25237305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2014.00019
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