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HYPOXIA INDUCED CHANGES IN EXPRESSION OF PROTEINS INVOLVED IN IRON UPTAKE AND STORAGE IN CULTURED LENS EPITHELIAL CELLS

Hypoxia inducible factor (HIF) regulates expression of over 60 genes by binding to hypoxia response elements (HRE) located upstream of the transcriptional start sites. Many genes encoding proteins involved in iron transport and homeostasis are regulated by HIF. Expression of iron handling proteins c...

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Autors principals: Goralska, Małgorzata, Fleisher, Lloyd N., McGahan, M. Christine
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154372/
https://ncbi.nlm.nih.gov/pubmed/24877740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.05.010
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