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HYPOXIA INDUCED CHANGES IN EXPRESSION OF PROTEINS INVOLVED IN IRON UPTAKE AND STORAGE IN CULTURED LENS EPITHELIAL CELLS
Hypoxia inducible factor (HIF) regulates expression of over 60 genes by binding to hypoxia response elements (HRE) located upstream of the transcriptional start sites. Many genes encoding proteins involved in iron transport and homeostasis are regulated by HIF. Expression of iron handling proteins c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4154372/ https://ncbi.nlm.nih.gov/pubmed/24877740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.05.010 |
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