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Genetic Control of Metabolism of Mutagenic Purine Base Analogs 6-Hydroxylaminopurine and 2-Amino-6-Hydroxylaminopurine in Yeast Saccharomyces cerevisiae
We studied the effect of inactivation of genes, which control biosynthesis of inosine monophosphate (IMP)de novo and purine salvage and interconversion pathways, on sensitivity of yeast Saccharomyces cerevisiae to the mutagenic and toxic action of 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylam...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4154312/ https://ncbi.nlm.nih.gov/pubmed/19514135 |
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