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Genetic Control of Metabolism of Mutagenic Purine Base Analogs 6-Hydroxylaminopurine and 2-Amino-6-Hydroxylaminopurine in Yeast Saccharomyces cerevisiae

We studied the effect of inactivation of genes, which control biosynthesis of inosine monophosphate (IMP)de novo and purine salvage and interconversion pathways, on sensitivity of yeast Saccharomyces cerevisiae to the mutagenic and toxic action of 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylam...

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Detalhes bibliográficos
Main Authors: Stepchenkova, E. I., Kozmin, S. G., Alenin, V. V., Pavlov, Yu. I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154312/
https://ncbi.nlm.nih.gov/pubmed/19514135
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