Atg7 deficiency impairs host defense against Klebsiella pneumoniae by impacting bacterial clearance, survival and inflammatory responses in mice

Klebsiella pneumoniae (Kp) is a Gram-negative bacterium that can cause serious infections in humans. Autophagy-related gene 7 (Atg7) has been implicated in certain bacterial infections; however, the role of Atg7 in macrophage-mediated immunity against Kp infection has not been elucidated. Here we sh...

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Detalhes bibliográficos
Main Authors: Ye, Yan, Li, Xuefeng, Wang, Wenxue, Ouedraogo, Kiswendsida Claude, Li, Yi, Gan, Changpei, Tan, Shirui, Zhou, Xikun, Wu, Min
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154251/
https://ncbi.nlm.nih.gov/pubmed/24993132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00046.2014
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