The ryanodine receptor is expressed in human pancreatic acinar cells and contributes to acinar cell injury

Physiological calcium (Ca(2+)) signals within the pancreatic acinar cell regulate enzyme secretion, whereas aberrant Ca(2+) signals are associated with acinar cell injury. We have previously identified the ryanodine receptor (RyR), a Ca(2+) release channel on the endoplasmic reticulum, as a modulato...

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Main Authors: Lewarchik, Christopher M., Orabi, Abrahim I., Jin, Shunqian, Wang, Dong, Muili, Kamaldeen A., Shah, Ahsan U., Eisses, John F., Malik, Adeel, Bottino, Rita, Jayaraman, Thottala, Husain, Sohail Z.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Pancreas
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154117/
https://ncbi.nlm.nih.gov/pubmed/25012845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00143.2014
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