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Antagonism of the prostaglandin E(2) EP1 receptor in MDCK cells increases growth through activation of Akt and the epidermal growth factor receptor
The actions of prostaglandin E(2) (PGE(2)) in the kidney are mediated by G protein-coupled E-prostanoid (EP) receptors, which affect renal growth and function. This report examines the role of EP receptors in mediating the effects of PGE(2) on Madin-Darby canine kidney (MDCK) cell growth. The result...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4154115/ https://ncbi.nlm.nih.gov/pubmed/25007872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00510.2013 |
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