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Antagonism of the prostaglandin E(2) EP1 receptor in MDCK cells increases growth through activation of Akt and the epidermal growth factor receptor

The actions of prostaglandin E(2) (PGE(2)) in the kidney are mediated by G protein-coupled E-prostanoid (EP) receptors, which affect renal growth and function. This report examines the role of EP receptors in mediating the effects of PGE(2) on Madin-Darby canine kidney (MDCK) cell growth. The result...

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書誌詳細
主要な著者: Taub, Mary, Parker, Robert, Mathivanan, Paremala, Ariff, Muhamad Asnawi Mohd, Rudra, Trina
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154115/
https://ncbi.nlm.nih.gov/pubmed/25007872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00510.2013
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