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PI3K/AKT Pathway Mediates Induction of IL-1RA by TSH in Fibrocytes: Modulation by PTEN

CONTEXT: TSH provokes expression of inflammatory genes in CD34(+) fibrocytes. These cells appear to infiltrate the orbit in Graves' disease (GD), where they putatively become the CD34(+) orbital fibroblast subset (GD-OF). This may have importance in solving the pathogenesis of thyroid-associate...

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Detalles Bibliográficos
Main Authors: Li, Bin, Smith, Terry J.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154109/
https://ncbi.nlm.nih.gov/pubmed/24840811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1257
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