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Adipose Tissue 12/15 Lipoxygenase Pathway in Human Obesity and Diabetes

CONTEXT: Visceral adipose tissue (VAT) is a key contributor to chronic inflammation in obesity. The 12/15-lipoxygenase pathway (ALOX) is present in adipose tissue (AT) and leads to inflammatory cascades that are causal for the onset of insulin resistance in rodent models of obesity. OBJECTIVE: The p...

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Main Authors: Lieb, David C., Brotman, Joshua J., Hatcher, Margaret A., Aye, Myo S., Cole, Banumathi K., Haynes, Bronson A., Wohlgemuth, Stephen D., Fontana, Mark A., Beydoun, Hind, Nadler, Jerry L., Dobrian, Anca D.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154098/
https://ncbi.nlm.nih.gov/pubmed/24955608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-4461
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