Adipose Tissue 12/15 Lipoxygenase Pathway in Human Obesity and Diabetes

CONTEXT: Visceral adipose tissue (VAT) is a key contributor to chronic inflammation in obesity. The 12/15-lipoxygenase pathway (ALOX) is present in adipose tissue (AT) and leads to inflammatory cascades that are causal for the onset of insulin resistance in rodent models of obesity. OBJECTIVE: The p...

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Main Authors: Lieb, David C., Brotman, Joshua J., Hatcher, Margaret A., Aye, Myo S., Cole, Banumathi K., Haynes, Bronson A., Wohlgemuth, Stephen D., Fontana, Mark A., Beydoun, Hind, Nadler, Jerry L., Dobrian, Anca D.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
JCEM Online: Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154098/
https://ncbi.nlm.nih.gov/pubmed/24955608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-4461
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