TPX2 knockdown suppressed hepatocellular carcinoma cell invasion via inactivating AKT signaling and inhibiting MMP2 and MMP9 expression

OBJECTIVE: Targeting protein for Xenopus kinesin-like protein 2 (TPX2) is a nuclear proliferation-related protein that plays a critical role in the formation of mitotic spindle. High expression of TPX2 has been observed in several types of tumors. However, the role of TPX2 in hepatocellular carcinom...

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Main Authors: Liu, Qingquan, Yang, Pinghua, Tu, Kangsheng, Zhang, Hongyong, Zheng, Xin, Yao, Yingmin, Liu, Qingguang
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153921/
https://ncbi.nlm.nih.gov/pubmed/25232213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.1000-9604.2014.08.01
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