GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft

Multiple lines of evidence suggest that the Sonic Hedgehog (Shh) signaling pathway is aberrantly reactivated in pancreatic cancer stem cells (CSCs). The objectives of this study were to examine the molecular mechanisms by which GANT-61 (Gli transcription factor inhibitor) regulates stem cell charact...

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Detalhes bibliográficos
Main Authors: Fu, Junsheng, Rodova, Mariana, Roy, Sanjit K., Sharma, Jay, Singh, Karan P., Srivastava, Rakesh K., Shankar, Sharmila
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153855/
https://ncbi.nlm.nih.gov/pubmed/23200667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.11.018
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