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Functional defects in NOD2 signaling in experimental and human Crohn disease

Increasing evidence suggests that a deficit in innate immunity may play a causative role in the pathogenesis of inflammatory bowel disease. The most compelling support for this hypothesis comes from the genetic association of Crohn disease (CD) with carriage of polymorphisms within the NOD2 gene, wh...

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Autors principals: Corridoni, Daniele, Arseneau, Kristen O, Cominelli, Fabio
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153771/
https://ncbi.nlm.nih.gov/pubmed/24637801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.28404
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