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Functional defects in NOD2 signaling in experimental and human Crohn disease

Increasing evidence suggests that a deficit in innate immunity may play a causative role in the pathogenesis of inflammatory bowel disease. The most compelling support for this hypothesis comes from the genetic association of Crohn disease (CD) with carriage of polymorphisms within the NOD2 gene, wh...

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Detalhes bibliográficos
Main Authors: Corridoni, Daniele, Arseneau, Kristen O, Cominelli, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153771/
https://ncbi.nlm.nih.gov/pubmed/24637801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.28404
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