The Oxidative Stress Product Carboxyethylpyrrole Potentiates TLR2/TLR1 Inflammatory Signaling in Macrophages

Oxidative stress is key in the pathogenesis of several diseases including age-related macular degeneration (AMD), atherosclerosis, diabetes, and Alzheimer's disease. It has previously been established that a lipid peroxidation product, carboxyethylpyrrole (CEP), accumulates in the retinas of AM...

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Detalhes bibliográficos
Main Authors: Saeed, Ali M., Duffort, Stephanie, Ivanov, Dmitry, Wang, Hua, Laird, James M., Salomon, Robert G., Cruz-Guilloty, Fernando, Perez, Victor L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153630/
https://ncbi.nlm.nih.gov/pubmed/25184331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106421
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