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Development of Transgenic Fungi That Kill Human Malaria Parasites in Mosquitoes

Metarhizium anisopliae infects mosquitoes through the cuticle and proliferates in the hemolymph. To allow M. anisopliae to combat malaria in mosquitoes with advanced malaria infections, we produced recombinant strains expressing molecules that target sporozoites as they travel through the hemolymph...

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Bibliografiske detaljer
Main Authors: Fang, Weiguo, Vega-Rodríguez, Joel, Ghosh, Anil K., Jacobs-Lorena, Marcelo, Kang, Angray, St. Leger, Raymond J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153607/
https://ncbi.nlm.nih.gov/pubmed/21350178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1199115
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