An immune-responsive serpin, SRPN6, mediates mosquito defense against malaria parasites

We have functionally analyzed the orthologous SRPN6 genes from Anopheles stephensi and Anopheles gambiae using phylogenetic, molecular, reverse genetic, and cell biological tools. The results strongly implicate SRPN6 in the innate immune response against Plasmodium. This gene belongs to a mosquito-s...

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Détails bibliographiques
Auteurs principaux: Abraham, Eappen G., Pinto, Sofia B., Ghosh, Anil, Vanlandingham, Dana L., Budd, Aidan, Higgs, Stephen, Kafatos, Fotis C., Jacobs-Lorena, Marcelo, Michel, Kristin
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283470/
https://ncbi.nlm.nih.gov/pubmed/16260729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508335102
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