An immune-responsive serpin, SRPN6, mediates mosquito defense against malaria parasites

We have functionally analyzed the orthologous SRPN6 genes from Anopheles stephensi and Anopheles gambiae using phylogenetic, molecular, reverse genetic, and cell biological tools. The results strongly implicate SRPN6 in the innate immune response against Plasmodium. This gene belongs to a mosquito-s...

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Autori principali: Abraham, Eappen G., Pinto, Sofia B., Ghosh, Anil, Vanlandingham, Dana L., Budd, Aidan, Higgs, Stephen, Kafatos, Fotis C., Jacobs-Lorena, Marcelo, Michel, Kristin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283470/
https://ncbi.nlm.nih.gov/pubmed/16260729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508335102
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