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Anopheles gambiae SRPN2 facilitates midgut invasion by the malaria parasite Plasmodium berghei

We report on a phylogenetic and functional analysis of genes encoding three mosquito serpins (SRPN1, SRPN2 and SRPN3), which resemble known inhibitors of prophenoloxidase-activating enzymes in other insects. Following RNA interference induction by double-stranded RNA injection, knockdown of SRPN2 in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Michel, Kristin, Budd, Aidan, Pinto, Sofia, Gibson, Toby J, Kafatos, Fotis C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369158/
https://ncbi.nlm.nih.gov/pubmed/16113656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400478
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