Transcriptional activation of human adult alpha-globin genes by hypersensitive site-40 enhancer: function of nuclear factor-binding motifs occupied in erythroid cells.

The developmental stage- and erythroid lineage-specific activation of the human embryonic zeta- and fetal/adult alpha-globin genes is controlled by an upstream regulatory element [hypersensitive site (HS)-40] with locus control region properties, a process mediated by multiple nuclear factor-DNA com...

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Hauptverfasser: Rombel, I, Hu, K Y, Zhang, Q, Papayannopoulou, T, Stamatoyannopoulos, G, Shen, C K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41536/
https://ncbi.nlm.nih.gov/pubmed/7604012
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