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Substrate specificity of transthyretin: identification of natural substrates in the nervous system

Besides functioning as the plasma transporter of retinol and thyroxine, TTR (transthyretin) is a protease, cleaving apoA-I (apolipoprotein A-I) after a phenylalanine residue. In the present study, we further investigated TTR substrate specificity. By using both P-diverse libraries and a library of p...

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Detalhes bibliográficos
Main Authors: Liz, Márcia A., Fleming, Carolina E., Nunes, Ana F., Almeida, Maria R., Mar, Fernando M., Choe, Youngchool, Craik, Charles S., Powers, James C., Bogyo, Matthew, Sousa, Mónica M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153561/
https://ncbi.nlm.nih.gov/pubmed/19138167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20082090
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