A Community-Based Multicenter Trial of Pharmacokinetically Guided 5-Fluorouracil Dosing for Personalized Colorectal Cancer Therapy

BACKGROUND. Pharmacokinetically guided (PK-guided) versus body surface area-based 5-fluorouracil (5-FU) dosing results in higher response rates and better tolerability. A paucity of data exists on PK-guided 5-FU dosing in the community setting. PATIENTS AND METHODS. Seventy colorectal cancer patient...

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Detalhes bibliográficos
Main Authors: Patel, Jai N., O’Neil, Bert H., Deal, Allison M., Ibrahim, Joseph G., Sherrill, Gary B., Olajide, Oludamilola A., Atluri, Prashanti M., Inzerillo, John J., Chay, Christopher H., McLeod, Howard L., Walko, Christine M.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2014
Assuntos:
Gastrointestinal Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153454/
https://ncbi.nlm.nih.gov/pubmed/25117066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0132
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