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Transcription Blockage by Bulky End-Termini at Single-Strand Breaks in the DNA Template: Differential Effects of 5′ and 3′ Adducts
RNA polymerases from phage-infected bacteria and mammalian cells have been shown to bypass single-strand breaks (SSBs) with a single nucleotide gap in the template DNA strand during transcription elongation; however, the SSB bypass efficiency varies significantly depending upon the backbone end-chem...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153415/ https://ncbi.nlm.nih.gov/pubmed/23066636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301240y |
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