Загрузка...

Transcription Blockage by Bulky End-Termini at Single-Strand Breaks in the DNA Template: Differential Effects of 5′ and 3′ Adducts

RNA polymerases from phage-infected bacteria and mammalian cells have been shown to bypass single-strand breaks (SSBs) with a single nucleotide gap in the template DNA strand during transcription elongation; however, the SSB bypass efficiency varies significantly depending upon the backbone end-chem...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Neil, Alexander J., Belotserkovskii, Boris P., Hanawalt, Philip C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153415/
https://ncbi.nlm.nih.gov/pubmed/23066636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301240y
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!